CLOBB (Cluster on the basis of BLAST similarity), is a clustering algorithm to identify and cluster ESTs.

CLOBB may be used incrementally, preserving original cluster designations. It tracks cluster-specific events such as merging, identifies 'superclusters' of related clusters and avoids the expansion of chimeric clusters. Based on the Perl scripting language, CLOBB is highly portable relying only on a local installation of NCBI's freely available BLAST executable.

References:
Making sense of EST sequences by CLOBBing them. John Parkinson, David B. Guiliano, and Mark Blaxter. Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, UK. BMC Bioinformatics. 2002; 3 (1): 31